The Resistance Files Spotlight: Methicillin-Resistant Staphylococcus aureus

Vastian Learning

Continuing Education Credits

: hour(s)

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Objectives

  • Describe the clinical significance and public health impact of methicillin-resistant Staphylococcus aureus (MRSA) in healthcare and community settings.
  • Explain the molecular mechanism of methicillin resistance, including the role of mecA/mecC genes and altered penicillin-binding proteins.
  • Identify appropriate laboratory methods for detecting MRSA and recognize common testing pitfalls that may lead to false susceptibility results.
  • Select recommended antimicrobial susceptibility testing methods for MRSA and apply appropriate reporting practices.
  • Summarize laboratory responsibilities related to infection control notification and communication when MRSA is detected.

Course Outline

  • MRSA
    • Clinical Relevance & Public Health Significance
    • Mechanisms of Resistance
    • Resistance Is Only Half the Story: Virulence Amplifies Impact
    • Identification Strategies
    • Workflow 1: Biochemical / Phenotypic Identification
    • Workflow 2: MALDI-TOF MS Identification
    • Workflow 3: Molecular Assays (mecA / mecC Detection)
    • Susceptibility Interpretation & Stewardship-Focused Reporting
    • Integrated Best-Practice Workflow
    • Infection Control & Notification Requirements
    • Key Takeaways
    • References

Additional Information

This is a mini course designed to enhance learning and reinforce existing knowledge. It does not provide continuing education (CE) credit. The purpose of this course is to support ongoing professional development and review.