Laboratory Evaluation of Iron Deficiency Anemia
Continuing Education Credits
Objectives
- Describe the incidence and etiology of iron deficiency anemia worldwide.
- Relate the importance of iron in the development of hemoglobin and oxygen delivery to the tissues.
- State the stages of development of iron deficiency anemia and identify key hematologic changes.
- Describe the purpose and principle of laboratory tests found in routine iron studies.
- Identify non-routine laboratory assays and state the principle of each used in the confirmation process of iron deficiency anemia.
- Differentiate iron deficiency anemia from other forms of anemia that may be similar in hematologic findings.
Course Outline
- Iron Deficiency Anemia Etiology and Incidence
- Introduction
- Incidence of Iron Deficiency Anemia
- Etiology of Iron Deficiency Anemia
- What percent of the cases of anemia worldwide were reported to be iron deficiency anemia?
- The recommended daily allowance for iron in an adult male is:
- Iron Metabolism and Its Role in Oxygen Delivery
- Iron Metabolism
- Heme Synthesis
- What form must iron be in to effectively carry oxygen?
- Duodenal cytochrome B (DCYTB) is involved in which of the following processes?
- Most dietary iron is found in which form?
- Stages of Iron Deficiency and Hematologic Changes
- Stages of Iron Deficiency Anemia
- Hematology Changes in Iron Deficiency Anemia
- Reticulocyte Hemoglobin Content
- Which of the following is the best early indicator of possible iron deficiency anemia?
- Routine Laboratory Assessment of Iron Deficiency Anemia
- Iron Studies
- Serum Iron
- Serum Iron Methodologies
- Total Iron Binding Capacity and Unsaturated Iron Binding Capacity
- Total Iron Binding Capacity and Unsaturated Iron Binding Capacity Methodologies
- Percent Saturation
- Serum Ferritin
- Serum Ferritin Methodologies
- Which of the following tests are considered to be a part of Iron Studies?
- Inflammation can falsely elevate what component of the iron studies panel?
- Additional Biomarkers of Laboratory Assessment of Iron Deficiency Anemia
- Zinc Protoporphyrin Testing
- Soluble Transferrin Receptor
- sTfR/log Ferritin Index
- Inflammatory Cytokines: Hepcidin
- Zinc protoporphyrin (ZPP) may be used as a screening test for iron deficiency anemia. Which of the following best explains the rationale for using ZPP in this context?
- Differentiation of IDA and Other Forms of Microcytic Anemia
- Differentiation of Microcytic Anemia
- Routine Hematologic Differentiation
- Hemoglobin Electrophoresis
- Presence or Absence of Pappenheimer Bodies
- Iron Studies Analysis of IDA Stages
- Summary: Differentiating IDA from Other Microcytic Anemias
- Summary
- References
- References
Additional Information
Level of Instruction: Intermediate
Intended Audience: Medical laboratory scientists, medical laboratory technicians, laboratory supervisors, and laboratory managers. This course is also appropriate for MLS and MLT students and pathology residents.
Author Information: Andrea Gordon, M.Ed., MLS(ASCP)SH, holds a Master's degree in Community Health Education from Plymouth State University and a Bachelor's degree in Medical Technology from the University of New Hampshire. She holds certification as a Medical Laboratory Scientist from the American Society of Clinical Pathology along with a Specialist in Hematology. Most of her career has been in the education of medical laboratory technicians and scientists after thirteen years in the clinical setting. She has over 25 years of experience as a Program Director for various laboratory science programs. She has approximately 5 years of experience as an administrator in higher education as a VP and Director of Education. Additionally, she has over 15 years of experience as a volunteer for NAACLS.Reviewer Information: Kaitlin Faughnan, MS, MLS(ASCP)CM, is currently an Assistant Professor at both SUNY Broome Community College and SUNY Upstate Medical University. At SUNY Broome, she teaches a comprehensive range of Medical Laboratory Science (MLS) subjects to Medical Laboratory Technician students. At SUNY Upstate Medical University, she specializes in teaching Immunohematology to Medical Laboratory Science students.
Professor Faughnan is actively engaged in curriculum development and revision, ensuring her courses remain at the forefront of laboratory science education. She also participates in initiatives aimed at raising awareness about the medical laboratory science profession and enhancing student recruitment in this field.
She received both a Bachelor of Science and a Master of Science in Clinical Laboratory Science. She holds New York state licensure and ASCP certification as a Medical Laboratory Scientist and previously worked as a generalist in a hospital setting.