How to Read a White Blood Cell Histogram
Continuing Education Credits
Objectives
- Describe the purpose, axes, and major cell regions of a 3-part white blood cell (WBC) histogram.
- Apply a systematic method to evaluate population distribution, peak separation, shoulders, extra peaks, and edge events.
- Recognize common histogram patterns associated with WBC predominance, abnormal cell populations, and analytical interference.
- Correlate WBC histogram findings with the total WBC count, absolute differential counts, analyzer flags, scattergrams, and peripheral blood smear findings.
Course Outline
- How to Read a White Blood Cell Histogram
- What is a White Blood Cell Histogram?
- Use a Systematic Reading Method
- Step 1: Locate the Expected Cell Regions
- Step 2: Assess the Shape and Separation
- Step 3: Examine the Edges and Possible Interference
- Step 4: Correlate Before Interpreting
- Table: Common Histogram Patterns
- Case Study
- Key Takeaways
- References
- References

