Urine Casts: Knowledge Check
Continuing Education Credits
Objectives
- Define the major types of urinary casts and the conditions under which they form.
- Integrate urine cast findings with other laboratory and clinical data to formulate a preliminary renal assessment.
Course Outline
- Summary of Urine Casts
- Table: Urinary Cast Summary
- Match each cast to its corresponding description.
- Case Studies
- A 62-year-old patient is admitted after a prolonged episode of hypotension following cardiac arrest. The patient's creatinine rises from 0.9 to 4.2 mg/dL over 48 hours. Urinalysis shows:Specific gravity: 1.010 Protein: 2+ Microscopic: numerous granular casts, several renal tubular epithelial (RTE) castsWhich diagnosis best explains these findings?
- A 28-year-old patient presents with tea-colored urine and facial swelling after a recent streptococcal infection. Urinalysis shows: Protein: 3+ Blood: 3+ Microscopy: dysmorphic RBCs, RBC casts What is the most likely diagnosis?
- A 36-year-old woman presents with fever, flank pain, and dysuria. Urinalysis shows: Leukocyte esterase: positive Nitrite: positive Microscopy: WBC casts What condition do the findings support?
- A 47-year-old patient presents with edema, frothy urine, and lab results showing: Serum albumin: 2.0 g/dL Urine protein: >3.5 g/day Microscopy: fatty casts, oval fat bodies, and cholesterol crystals with Maltese cross appearanceWhat condition best explains these findings?
- A 71-year-old patient with long-standing hypertension presents with declining renal function. Labs reveal: Creatinine: 6.3 mg/dL eGFR: 8 mL/min Urine microscopy: broad waxy casts What do these findings indicate?
- A 54-year-old male has been on high-dose aminoglycosides for 10 days. He develops rising creatinine and oliguria. Urinalysis shows: Specific gravity: low Microscopy: numerous RTE cells and RTE casts What is the most likely mechanism?
- A healthy 24-year-old athlete presents for a routine physical. He ran 12 miles earlier in the day. Urinalysis shows: Trace protein Few hyaline casts No hematuria No WBCs What is the correct interpretation?

